In the 12 meetings played between the clubs since 2012, the Cobblers have won seven, drawn two, and lost only three.
The current season saw honours even, with Exeter winning 3-2 at St James Park and the Cobblers triumphing 2-0 at the PTS Academy Stadium at the end of February, just two weeks before the Covid-19 enforced lockdown.
But by and large this is a fixture in which the Cobblers have held the upper hand in recent times, and indeed their overall League record against the Grecians, stretching back to 1920, is also pretty impressive.
In 117 matches between the clubs, Town have won 53 and drawn 34, losing 30.
Here, we take a pictorial look at the past 12 meetings between the sides, starting with a comprehensive win for Aidy Boothroyd's Town at Sixfields back in October, 2012...
All pictures by Pete Norton.
1. Oct, 2012: Cobblers 3 Exeter City 0
A comfortable win for the Cobblers at Sixfields thanks to goals from Adebayo Akinfenwa, Kelvin Langmead and Alex Nicholls, Photo: Pete Norton
2. March, 2013: Exeter City 3 Cobblers 0
Bad day for Wembley-bound Cobblers as they are thumped at St James Park, with goals from Jamie Cureton (see pic), Jake Gosling and a Lee Nicholls own goal Photo: Pete Norton
3. September, 2013: Cobblers 1 Exeter City 2
Jacob Blyth fired Town into an early lead, but the Grecians hit back and won it with John O'Flynn's last-minute header (see pic) Photo: Pete Norton
4. March, 2014: Exeter City 0 Cobblers 1
Ian Morris scored the only goal as new manager Chris Wilder's team secured a precious win on their way to Football League survival Photo: Pete Norton