In the 12 meetings played between the clubs since 2012, the Cobblers have won seven, drawn two, and lost only three.
The current season saw honours even, with Exeter winning 3-2 at St James Park and the Cobblers triumphing 2-0 at the PTS Academy Stadium at the end of February, just two weeks before the Covid-19 enforced lockdown.
But by and large this is a fixture in which the Cobblers have held the upper hand in recent times, and indeed their overall League record against the Grecians, stretching back to 1920, is also pretty impressive.
In 117 matches between the clubs, Town have won 53 and drawn 34, losing 30.
Here, we take a pictorial look at the past 12 meetings between the sides, starting with a comprehensive win for Aidy Boothroyd's Town at Sixfields back in October, 2012...
All pictures by Pete Norton.
5. August, 2014: Cobblers 1 Exeter City 0
Marc Richards scored a spectacular overhead kick in the 89th-minute to secure a win for the Cobblers Photo: Pete Norton
6. January, 2015: Exeter City 0 Cobblers 2
First-half goals from Marc Richards and John-Joe O'Toole secured the win for a resurgent Town Photo: Pete Norton
7. August, 2015: Cobblers 3 Exeter City 0
With no sign of the impending financial crisis, Town dispatched Exeter 3-0 thanks to a stunning Jason Taylor strike and goals from Ryan Cresswell and Marc Richards Photo: Pete Norton
8. April, 2016: Exeter City 0 Cobblers 0
A drab draw, but it was still party time in Devon as the Cobblers clinched the Sky Bet League Two title Photo: Pete Norton