One player that especially stands out is Ivan Toney, who came through the Northampton youth ranks in 2012 before blasting his way to the Premier League and the England squad.
Some players have done that in reverse as they drop down the leagues, with Marco Gabbiadini being one such player of note.
Here we take a look at 19 top ex-Cobblers who tasted life at the top of the game.
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9. Christopher Missilou
Christopher Missilou had a bit-part role for Northampton Town in the 2020/21 campaign, playing 15 games. He came through the youth ranks at Auxerre and played one game in Ligue 1. Photo: Pete Norton
10. Kemar Roofe
Kemar Roofe is now a big name at Glasgow Rangers, but few will probably remember his brief six game loan spell at Cobblers in 2012. He also played top flight football in Belgium with Anderlecht. Photo: Pete Norton
11. Robert Ullathorne
Robert Ullathorne played 13 times for Cobblers in the 2004 season. He is of course better remembered for his Premier League spells with Norwich City and Leicester City between 1990 and 2000. Photo: Pete Norton
12. Simon Cox
Simon Cox played nine games for Cobblers in the 2007 during a loan from Reading. He would later join West Brom and played 22 Premier League games for the club in the 2010/11 season. Photo: Julian Finney