The two clubs haven't met for five years, with their most recent clash a 1-0 for Town in Sky Bet League Two in December, 2015.
Marc Richards was the man with the only goal on that occasion, and it maintained a good run of results for the Cobblers against Stanley.
Following their return to the League in 2006, Stanley played Town for the first time in more than 48 years in August, 2009 - but they were soon to become familiar foes.
They would go on to play each other 14 times in the next six-and-a-half years, and it would be the Cobblers who would have the upper hand.
In those 14 encounters, Town won eight, drew three and lost three, with their record against Stanley at Sixfields reading P 7 W 4 D 2 L 1.
Ahead of Saturday's showdown at the PTS Academy Stadium, we have taken a look through photographer Pete Norton's archives and recall those past 14 meetings.
9. Nov 30, 2013: Cobblers 1 Stanley 0
Stuart Dallas (29) scored the only goal to secure what would be Aidy Boothroyd's final win as Cobblers manager Photo: Pete Norton
10. April 5, 2014: Stanley 0 Cobblers 1
Chris Hackett (4) scored the only goal as Chris Wilder's Town claimed a crucial win on their way to the 'Great Escape' on the final day of the season Photo: Pete Norton
11. Sept 20, 2014: Cobblers 4 Stanley 5
Town came out on the wrong end of a nine-goal thriller at Sixfields... On target for Cobblers were Marc Richards (26)m, Ivan Toney (78, 89) and Darren Carter (90) Photo: Pete Norton
12. Jan 31, 2015: Stanley 1 Cobblers 5
The birth of a the 'dream team'... Town winning despite Ryan Creswell's first-half sending off. On target were Ricky Holmes (5), March Richards (pen 32, 67) and Lawson D'Ath (65, 80) Photo: Pete Norton