It will be far from easy with Cambridge having rallied in recent weeks to get back into the survival hunt.
But Cobblers will go into the game in confident mood after two encouraging away draws in their last two outings.
It promises to be another entertaining round of action across the league, with these results the predicted outcome according to the latest AI predictions.
Let us know your thoughts on the game and get the latest Cobblers news on our website.


10. Northampton Town 2 Cambridge United 1
Home: 41% Draw: 28% Away: 31% Photo: Getty Images


12. 2024 Getty Images : Wrexham 2 Exeter City 1
STOCKPORT, ENGLAND - NOVEMBER 16: Jon Daei Boevarsson of Wrexham looks on during the Sky Bet League One match between Stockport County FC and Wrexham AFC at Edgeley Park on November 16, 2024 in Stockport, England. (Photo by Ben Roberts Photo/Getty Images) : Home: 47% Draw: 29% Away: 24% Photo: Getty Images : f