Northamptonshire will not be offering new contracts to Kyle Coetzer or Maurice Chambers.
The pair leave the County Ground having figured as no more than fringe players during the 2015 season.
Scotsman Coetzer arrived at Northamptonshire - initially on loan - from Durham in 2011.
He went on to play 42 first-class matches scoring 1,777 runs at an average of 27.33.
He also played 31 one-day games and had 32 Twenty20 appearances.
Former Essex and Warwickshire paceman Chambers was given a two-year deal with the County at the start of last season.
However he made just 21 first-team appearances in all forms of the game during his spell at the club.
The Steelbacks’ head coach David Ripley said: “These are always difficult decisions to make regarding players’ futures.
“Kyle has been a model professional during his time here, he deals with success and failure in equal measure, a very valuable thing in a cricket dressing-room.
“We wish him and his family well in the future.
“After a slow start in 2014, Maurice has put in a big effort this year but has been unable to get past our other seam bowlers and play regularly in the first-team.”