Motorists are being advised to avoid the A6 northbound after a crash involving two vehicles.
Police, fire and ambulances services, including the air ambulance, were called to the A6 just outside Rushden at 12.25pm today (Monday).
A police spokesman said one person was taken to Bedford Hospital and a further two people were taken to Kettering General Hospital for treatment, although the injuries are not thought to be life-threatening.
The spokesman added: “We are just in the process of organising recovery of the vehicles involved and there’s oil on the road.
“Road closures are in place, which are causing a few problems, so we would urge people to avoid the A6 northbound for a couple of hours.”