Almost every student at Northampton School for Girls passed two or more A-levels.
Julia Harley, headteacher, said she was thrilled with the “outstanding success” of a number of students.
She said: “A great many students secured places at a range of the country’s most prestigious universities and a number have achieved far higher than expected.
“Once again, it is thrilling to see so many students be successful in gaining their first choice of university.”
To performing students included Rhiannon Dunkerley who achieved two As and one A* and is going to study Speech and Language Therapy at the University of East Anglia.
The teenager said: “I did better than I expected. I was shocked when I opened my results.”
The two school presidents, Hayley Hall and Maggie Symonds, achieved two A*s and 2 As and four As, respectively. They are both going to study medicine at university.
Assistant Headteacher, Jane MacDonald said: “The range of subjects our students are going on to study at university is impressive. It shows that girls can be successful in all subjects, even those traditionally associated with boys.
“This year we have girls embarking on degrees in architecture, paramedic science, chemical engineering, mechanical engineering, neuroscience, genetics and motorsport and international relations.
In AS level, 86 per cent of students gained three or more grades at A* to E.
New school president Heather Hobbs achieved four As, as did Hayley Wagstaff. Other students who also achieved four As included Cleo Annandale, Sophie Battison, Khaleda Begum, Arianne Delos-Santos, Tiana Gordon, Mairead Harrison and Sara Stevenson.
Carly Waterman, deputy headteacher, said, “Once again we have a large number of girls who are aiming to apply to the very best universities in the country.
“Their AS level results give them an excellent head start. Credit must, as always, go to teachers, parents and to the students themselves, who work extremely hard and show such determination.”
The school also praised students who have achieved excellent grades in the face of difficult circumstances, including Atarah Green, who is going to Aston University to study Psychology and Sociology and Gina Strausa who is going to Royal Holloway to read English and Creative Writing.
Paul Smith, Assistant Headteacher said, “Life has a way of throwing up all kinds of obstacles, but our girls always manage to face adversity with courage and grace. To see them achieve such success makes us very proud.”