A 35-year-old woman suffered a serious head injury after a collision on the M1 in Northamptonshire.
The crash happened shortly before 3am on the M1 northbound, just north of junction 15 on Saturday.
A silver Vauxhall Zafira, driven by a 39-year-old man from Leamington Spa, was in collision with a lorry, driven by a 44-year-old man from Ilkeston in Derbyshire.
A 35-year-old woman, also from Leamington Spa, who was a passenger in the Zafira, was taken to University Hospital Coventry with a serious head injury.
Witnesses to this incident, or anyone who has any information, is asked to contact Northamptonshire Police on 101 or call the Drivewatch Hotline on 0800 174615.