A planned development of 2,000 homes will provide schools, shops and jobs as well as paving the way for the dualling of part of the A43, a council report says.
Barratt Homes is due to submit a planning application imminently for the site on the outskirts of Northampton, which sits to the east of the A43, with Moulton to the west, and the Round Spinney industrial estate to the south.
Northamptonshire County Council said the site could create 650 permanent jobs and 3,000 construction jobs.
The plans include provision for a food store, pub, day nursery, medical centre, five retail units and an industrial unit.
There will also be two primary schools, outdoor sports pitches, allotments and a children’s play area.
And the proposal includes creating a new section of dual carriageway, to run between the Moulton roundabout and Sywell roundabout.
The county council announced in July that it wanted to build a dual carriageway from Moulton to Sywell, following on from an announcement in January about plans for a Moulton bypass.
Councillor Andre Gonzalez de Savage (Con, East Hunsbury and Shelfleys), said the scheme would be reliant on developer funding, and would bring major benefits to the area.
He said: “We are looking at around 650 jobs and £45 million additional revenue. The biggest impact for us locally will be construction jobs.
“It is sensible and realistic to develop homes in this area.
“There is absolutely going to be disruption in the short term and residents will not be happy. But there is a long-term benefit.
“I will always back quality development in the right area at the right time,” he added.
Northampton Borough Council is set to devolve the decision-making on the application to Daventry District Council, as most of the site is within its boundary.