Jeanette Crizzle, 51, died in October after a year-long search to find a suitable bone marrow donor failed.
The Jeanette Crizzle Trust, launched by Adam, 43, and their two children, Emily, 16, and Nicholas, 14, will raise public awareness of the need for bone marrow, blood and organ donors by gathering research.
Today marks the official launch of the trust in the UK but Mr Crizzle hopes to eventually roll the project out across the world.
He said: "Even up to her death in October last year, not once did Jeanette complain, blame or rebel. She was a remarkable lady."
He added: "It's not been an easy year but what has come out of it is quite major.
"I think the major thing is to get the project launched in as many countries as possible and raise the percentages of people who donate blood, bone marrow and organs."
Over the next 20 years Mr Crizzle plans to take the project over to America and then on to the rest of the world.
Prime Minister Tony Blair has already backed the Jeanette Crizzle Trust in a speech in the House of Commons.
In September the Government is to launch an education programme on the importance of blood, organ and bone marrow donors in 6,000 secondary schools.
Mr Crizzle said the trust would monitor the Government's programme, which could be named after Jeanette.
The trust will submit annual reports to the Health Minister and Shadow Health Minister each year to ensure the number of donors increases.
Mr Crizzle said: "Our 20-year strategic plan will take us next to the United States and, using the evidence from our annual reports, endeavour to persuade Congress to take on board a similar education programme.
"If successful, this organisation will build relationships with governments internationally so that the same programme can be accepted globally in the long term."
Anyone who wishes to help the trust monitor the amount of donors in the UK can log onto the trust's website and fill in the brief questionnaire.
Businesses wishing to sponsor the trust should also get in touch.
The trust will be launched in the Rutland Suite at Kettering Park Hotel at 3pm.
Mr Crizzle's launch speech:
Twelve months ago nearly to the day, Jeanette and I had to take a very deep breath when we were informed that due to her mixed racial background of Greek, Italian and English, it was going to be a problem to find a donor for her. Three months earlier we had received the shocking news that she was suffering from Acute Myeloid Leukaemia. All of this was on top of a serious mountain accident in Switzerland two months before and I confess that at that time, both the children and I thought we had lost her.

One could say 'Oh my goodness' what other calamity can unfold?" Yet despite all of this even up to her death in October last year, not once did Jeanette complain, blame or rebel. A remarkable lady, but then perhaps I am biased.

After that time twelve months ago, when we were told that they could not find a donor, I decided to look into why this was. Surely on a planet of 6.5 billion people there was someone who could match her bone marrow.

Research involving the interviewing of nearly 400 members of the public was followed by research in schools with nearly 400 sixth formers by Mike Mallalieu, Head of Science at Jeanette's school. This particular data showed that when students were asked at first if they would be a donor only 26% said yes. A presentation followed, covering the facts, after which the same question was put to them again. Interestingly, the ones who said YES increased from 26% to 90%. Further to this, the ones who were 'NOT SURE' dropped from 66% to 3%.

All of this showed that while ignorance was widespread amongst the general public as a whole with regard to donation, if children were given the correct information while at school their impact on society could be significant in the long term.

With the research reports complete and full support from our MP Philip Hollobone, meetings followed with Rosie Winterton, Health Minister and John Baron Shadow Health Minister in April of last year. A month later the Minister agreed with the key proposal of our report and was committed to setting up an education programme in all 6000 secondary schools in the UK to cover education about Blood, Organ and Bone Marrow donation.

The purpose of the Jeanette Crizzle Trust is to measure the effectiveness of this education programme through questionnaires and report our findings annually to the Health Minister. This will enable us to make suggestions for improving the programme, should we find the donor registers are not being added to.

What are the long term implications of our work? Well, let us look at costs for Kidney Transplants, just as an example.

? Between 2005 and 2006, 1,914 people received a kidney transplant. These transplants are now saving the NHS £46.1m in dialysis costs each year for every year that the new kidney functions.
? On 1 January 2007 there were 6,200 patients on dialysis waiting for a transplant, costing the taxpayer around £190m per annum. If all of these patients received a transplant, the approximate cost would be £40m per annum, which represents a saving to the NHS of £150m per year.

What about the challenges?

? Well even though 23% of the UK population carry a donor card, 40% of bereaved relatives refuse to donate.

We all benefit from this education programme which covers every area of donation. Apart from the patients who need donors so that they can have a new lease of life, the savings gained can be used in other areas of the NHS which are in desperate need.

Our 20 year strategic plan will take us next to the United States and, using the evidence from our annual reports, endeavour to persuade Congress to take on board a similar education programme. If successful, this organisation will build relationships with governments internationally, so that the same programme can be accepted globally in the long term.

Jeanette's death was, for me, a loss that can never be replaced. Yet, this organisation being launched today means that thousands of people in the future will benefit from the work of the Jeanette Crizzle Trust.